Dysport produces intrinsically more swallowing problems than Botox: unexpected results from a conversion factor study in cervical dystonia
نویسندگان
چکیده
منابع مشابه
Respective potencies of Botox and Dysport: a double blind, randomised, crossover study in cervical dystonia.
OBJECTIVES Botulinum toxin type A is a potent neuromuscular paralyzing agent used in various disorders including cervical dystonia. Two preparations of botulinum toxin are now commercially available ( Dysport and Botox), but much controversy remains about their respective potencies. The aim of the study was to compare the efficacy of Botox with two different ratios of Dysport. METHODS A doubl...
متن کاملDysport and Botox at a Ratio of 2.5:1 Units in Cervical Dystonia: A Double-Blind, Randomized Study
We aimed to compare Dysport (abobotulinumtoxinA, Ipsen Biopharm, Slough, UK) and Botox (onabotulinumtoxinA, Allergan, Irvine, CA, USA) at a 2.5:1 ratio in the treatment of cervical dystonia (CD). A Dysport/Botox ratio of lower than 3:1 was suggested as a more appropriate conversion ratio, considering its higher efficacy and more frequent incidence of adverse effects not only in the treatment of...
متن کاملConversion Ratio between Botox®, Dysport®, and Xeomin® in Clinical Practice.
Botulinum neurotoxin has revolutionized the treatment of spasticity and is now administered worldwide. There are currently three leading botulinum neurotoxin type A products available in the Western Hemisphere: onabotulinum toxin-A (ONA) Botox(®), abobotulinum toxin-A (ABO), Dysport(®), and incobotulinum toxin A (INCO, Xeomin(®)). Although the efficacies are similar, there is an intense debate ...
متن کاملOnabotulinumtoxinA (Botox®) and AbobotulinumtoxinA (Dysport®) Esansiyel Blefarospazm Tedavisinde Botox® ve Dysport® un Uzun Dönem Sonuçları
Objective:To compare the clinical characteristics and outcomes of patients with blepharospasm who were treated with OnabotulinumtoxinA (Botox®) and AbobotulinumtoxinA (Dysport®). Methods: A total of 100 eyes of 78 patients who were diagnosed with blepharospasm were evaluated during a retrospective, randomized, parallel group study. The severity of spasm, eyelid closing force, and functional vis...
متن کاملBotox and Dysport: is there a dose conversion ratio in dermatology and aesthetic medicine?
To the Editor: The use of botulinum neurotoxin A is the most frequent intervention in aesthetic medicine. Sales of the two main preparations—Botox (Allergan Inc, Irvine, CA) and Dysport (Ipsen Ltd, Slough, Berkshire, UK)—amounted to USD $1 billion in 2007, and the trend is still growing. Even after 15 years of clinical use, the unit equivalence between these two main botulinum neurotoxin A prod...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 2002
ISSN: 0022-3050
DOI: 10.1136/jnnp.73.5.604